Glucocorticoid Steroids Desonide CAS 638-94-8 for Anti-inflammatory

Glucocorticoid Steroids Desonide CAS 638-94-8 for Anti-inflammatory

Desonide

Synonyms: PREDNACINOLONE;DESONIDE;1,4-PREGNADIEN-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE;(11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione;16-alpha-hydroxyprednisole-16,17-acetonide;17-acetonide,16-alpha-hydroxy-prednisolone-1;d-2083;steroderm 
CAS: 638-94-8 
MF: C24H32O6 
MW: 416.51 
EINECS: 211-351-6 

Chemical Properties Off-White Solid 
Usage antifungal 
Usage Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).

Desonide Description:

Desonide Ointment, 0.05% contains Desonide (Pregna - 1,4 - diene - 3,20 - dione,11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - ,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents.

Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:

The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.

Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.

Desonide Applications:

This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis,allergies, rash). Desonide reduces the swelling, itching and redness that can occur in these types of conditions. Desonide is a mild corticosteroid.

Desonide Ointment, 0.05% is a low potency corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.

It should not be used for longer than two weeks unless directed by a physician.